@article { 2126,
	title = {Mapping H5N1 highly pathogenic avian influenza risk in Southeast Asia},
	journal = {PNAS},
	year = {2008},
	abstract = {The  highly  pathogenic  avian  inﬂuenza  (HPAI)  H5N1  virus  that
emerged in southern China in the mid-1990s has in recent years
evolved into the ﬁrst HPAI panzootic. In many countries where the
virus was detected, the virus was successfully controlled, whereas
other countries face periodic reoccurrence despite signiﬁcant con-
trol efforts. A central question is to understand the factors favoring
the continuing reoccurrence of the virus. The abundance of do-
mestic ducks, in particular free-grazing ducks feeding in intensive
rice cropping areas, has been identiﬁed as one such risk factor
based on separate studies carried out in Thailand and Vietnam. In
addition, recent extensive progress was made in the spatial pre-
diction of rice cropping intensity obtained through satellite imag-
ery  processing.  This  article  analyses  the  statistical  association
between the recorded HPAI H5N1 virus presence and a set of ﬁve
key environmental variables comprising elevation, human popu-
lation, chicken numbers, duck numbers, and rice cropping intensity
for three synchronous epidemic waves in Thailand and Vietnam. A
consistent pattern emerges suggesting risk to be associated with
duck abundance, human population, and rice cropping intensity in
contrast to a relatively low association with chicken numbers. A
statistical risk model based on the second epidemic wave data in
Thailand is found to maintain its predictive power when extrap-
olated to Vietnam, which supports its application to other coun-
tries with similar agro-ecological conditions such as Laos or Cam-
bodia. The model’s potential application to mapping HPAI H5N1
disease risk in Indonesia is discussed.},
	URL = {http://www.pnas.org/cgi/doi/10.1073/pnas.0710581105},
	author = {Marius Gilbert and Xiangming Xiao and Dirk U. Pfeiffer and M. Epprecht and Stephen Boles and Christina Czarnecki and Prasit Chaitaweesub and Wantanee Kalpravidh and Phan Q. Minh and M. J. Otte and Vincent Martin and Jan Slingenbergh}
}

